Research Roundup: Is CBD Withdrawal a Thing?

The potential therapeutic benefits of CBD are endless. We've talked about that on the blog, and we continue to update you with the latest on CBD. There is no denying that the CBD boom has created a sense of normalcy in the consciousness of the masses, something that would be impossible ten years ago. With the distinction that CBD does not give a "high" like THC, people are more open to trying CBD products, and many swear to the therapeutic benefits and relief from a variety of illnesses.

With a lot of attention and research on CBD as potential treatments for illnesses such as anxiety, epilepsy, and pain, other types of addiction-related researches have surfaced. CBD might be a possible solution to addiction-related withdrawal symptoms according to clinical trials, but a question remains unanswered. Will the use of CBD produce withdrawal symptoms of its own?

Cannabis, Alternative for Opioid-Based Pain Medication?

The research using cannabis as a potential treatment for opioid withdrawal has been a subject for years. A review on cannabis research in 2018, but Not CBD directly, showed cannabis as a possible alternative to opioids for chronic pain management. The use of cannabis as an opiate substitute for chronic pain management can be found in many studies. However, the lack of comparison trials between opiate-based and cannabis-based chronic pain treatments are not enough to produce conclusive results.

CBD and Opioid Addiction

There is an epidemic in the United States. The availability of prescription opioid medications has resulted in 400,000 deaths in the past ten years with about 25% of patient abusing their opioid prescriptions. Current opioid drugs target the same mu-opioid receptor as heroin and morphine. These medications are highly regulated and carry a stigma and the risk of addiction. There is a drive to seek alternative treatments that do not target the mu-receptors, decreasing the chances of addiction and death. And for those who are addicted, we wanted to help them with anxiety and cravings associated with relapse.

A 2019 study proposed CBD might be able to reduce cravings due to opioid addiction. The objective of the study was to investigate the potential effects of CBD on curbing opioid craving and reducing anxiety, two factors that contribute to most relapses of recovering heroin users. The study aimed to assess the potential of CBD on craving and anxiety in heroin-addicted individuals. A group of men and women, all with a history of heroin abuse but not current users, were given either CBD or a placebo. The study included the showing of videos containing neutral and heroin use. Compared to participants that received a placebo, those given CBD had reduced drug cue-induced craving and anxiety from the shown videos. The use of CBD has proved to be an excellent alternative for opioids. 

High stress and anxiety levels often are the causes of relapse in drug addicts. A study reduced the risk in alcohol and cocaine relapse instances when given CBD. If you are considering the use of CBD as an alternative to opioid medication, please consult with a doctor.

Does CBD Cause Withdrawal Symptoms?

Any human activity, whether routine or habit, can be addictive. Does that apply to CBD use? Technically, the term psychoactive is associated with CBD. It interacts with the endocannabinoid system affecting brain functions related to mood and cognitive functioning. Although CBD is non-intoxicating (does not cause a high), because it is associated with cannabis, there is still some “reefer madness” ideas sticking around where people think CBD can make you high, cause addiction, and withdrawal.

A new study put the withdrawal aspect to the test. This study used 30 healthy individuals who received 750mg CBD (as Epidiolex) twice a day for a total of 1500mg a day over the course of 4 weeks. Afterwards, they were split into two groups. One group continued to receive the same amount of CBD while the other group got a placebo with nothing. This placebo group would serve as our observation for withdrawal effects. The study concludes, “In healthy volunteers, no evidence of withdrawal syndrome was found with abrupt discontinuation of short-term treatment with CBD.”

CBD study is still in its infancy. Even with the CBD boom, there is a lack of research regarding long term use. What researchers found promising about CBD is the potential to affect withdrawal symptoms from other drugs. CBD is considered very safe. At, we continuously learn about the benefits of CBD. All the CBD products for sale on the site that go through rigorous testing. We make sure they are safe.

Cannabis researchers and scientists are discovering something new every day. Who knows what's next for CBD? We will keep you updated.